Characterization of HGF/Met Signaling in Cell Lines Derived From Urothelial Carcinoma of the Bladder

There is mounting evidence of oncogenic hepatocyte growth factor (HGF)/Met signaling in urothelial carcinoma (UC) of the bladder. The effects of three kinase inhibitors, cabozantinib, crizotinib and EMD1214063, on HGF-driven signaling and cell growth, invasion and tumorigenicity were analyzed in cul...

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Bibliographic Details
Main Authors: Young H. Lee, Andrea B. Apolo, Piyush K. Agarwal, Donald P. Bottaro
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/6/4/2313