STAT3 and SOX-5 induce BRG1-mediated chromatin remodeling of RORCE2 in Th17 cells

STAT3 and SOX-5 induce BRG1-mediated chromatin remodeling of RORCE2 in Th17 cells

Abstract Retinoid-related orphan receptor gamma t (RORγt) is the lineage-specific transcription factor for T helper 17 (Th17) cells. Our previous study demonstrated that STAT3 likely participates in the activation of RORCE2 (a novel enhancer of the RORγt gene) in Th17 cells. However, the detailed me...

Full description

Bibliographic Details
Main Authors: Xian Wang, Chao Han, Di Yang, Jian Zhou, Hui Dong, Zhiyuan Wei, Shuai Xu, Chen Xu, Yiwei Zhang, Yi Sun, Bing Ni, Sheng Guo, Jingbo Zhang, Tingting Zhao, Xiangmei Chen, Jie Luo, Yuzhang Wu, Yi Tian
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05735-9

Internet

https://doi.org/10.1038/s42003-023-05735-9

Similar Items