Single sample scoring of molecular phenotypes

Single sample scoring of molecular phenotypes

Abstract Background Gene set scoring provides a useful approach for quantifying concordance between sample transcriptomes and selected molecular signatures. Most methods use information from all samples to score an individual sample, leading to unstable scores in small data sets and introducing bias...

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Bibliographic Details
Main Authors: Momeneh Foroutan, Dharmesh D. Bhuva, Ruqian Lyu, Kristy Horan, Joseph Cursons, Melissa J. Davis
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
Single sample
Gene set score
Singscore
Gene signature
Gene set enrichment
Transcriptome
Online Access:http://link.springer.com/article/10.1186/s12859-018-2435-4

Internet

http://link.springer.com/article/10.1186/s12859-018-2435-4

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