A TWO-YEAR STUDY OF CANCEROGENIC POTENTIAL OF THE NEW OPIOID RECEPTOR ANTAGONIST ONDELOPRAN IN RATS

A TWO-YEAR STUDY OF CANCEROGENIC POTENTIAL OF THE NEW OPIOID RECEPTOR ANTAGONIST ONDELOPRAN IN RATS

Opioid receptor antagonists are widely used for the treatment of alcohol dependence. Currently, original drug Odelepran (INN: ondelopran) with a unique binding profi le to all three types of human opioid receptors (μ, κ, δ) is being developed by R-Pharm.Aim of the study. To investigate a cancerogenic...

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Bibliographic Details
Main Authors: K. L. Kryshen, A. A. Muzhikyan, D. S. Gaidai, K. O. Zaikin, A. E. Katelnikova, M. Yu. Samsonov, E. I. Mukhametshina, G. E. Konopleva, E. V. Shipaeva, A. A. Dmitrieva, F. S. Shagiakhmetov, A. O. Popova, M. N. Makarova, V. G. Makarov
Format: Article
Language:Russian
Published: QUASAR, LLC 2019-06-01
Series:Исследования и практика в медицине
Subjects:
alcohol dependence
opioid receptor antagonist
ondelopran
carcinogenicity
incidence of tumors
rats
Online Access:https://www.rpmj.ru/rpmj/article/view/400

Internet

https://www.rpmj.ru/rpmj/article/view/400

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