Stereodivergent dehydrative allylation of β-keto esters using a Ru/Pd synergistic catalyst

α-Alkylation of β-keto esters is a frequently used reaction for carbon–carbon bond formation, but a general, stereoselective version of this reaction is challenging to realize. Here, the authors report a combined ruthenium and palladium catalytic system for the asymmetric dehydrative condensation be...

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Bibliographic Details
Main Authors: Thien Phuc Le, Shinji Tanaka, Masahiro Yoshimura, Kazuhiko Sato, Masato Kitamura
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33432-4