Development of a Novel Anti-CD44 Variant 5 Monoclonal Antibody C<sub>44</sub>Mab-3 for Multiple Applications against Pancreatic Carcinomas

Pancreatic cancer exhibits a poor prognosis due to the lack of early diagnostic biomarkers and the resistance to conventional chemotherapy. CD44 has been known as a cancer stem cell marker and plays tumor promotion and drug resistance roles in various cancers. In particular, the splicing variants ar...

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Bibliographic Details
Main Authors: Yuma Kudo, Hiroyuki Suzuki, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/12/2/31