Novelty Search Promotes Antigenic Diversity in Microbial Pathogens

Novelty Search Promotes Antigenic Diversity in Microbial Pathogens

Driven by host–pathogen coevolution, cell surface antigens are often the fastest evolving parts of a microbial pathogen. The persistent evolutionary impetus for novel antigen variants suggests the utility of novelty-seeking algorithms in predicting antigen diversification in microbial pathogens. In...

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Bibliographic Details
Main Authors:	Brandon Ely, Winston Koh, Eamen Ho, Tasmina M. Hassan, Anh V. Pham, Weigang Qiu
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Pathogens
Subjects:	surface antigen antigenic variation fitness landscape evolution genetic algorithm novelty search
Online Access:	https://www.mdpi.com/2076-0817/12/3/388

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