Aged mice ovaries harbor stem cells and germ cell nests but fail to form follicles

Abstract Background We recently published evidence to suggest that two populations of stem cells including very small embryonic-like stem cells (VSELs) and ovarian stem cells (OSCs) in ovary surface epithelium (OSE) undergo proliferation/differentiation, germ cell nests (GCN) formation, meiosis and...

Full description

Bibliographic Details
Main Authors: Diksha Sharma, Deepa Bhartiya
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-022-00968-4