Klotho’s impact on diabetic nephropathy and its emerging connection to diabetic retinopathy

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide and is a significant burden on healthcare systems. α-klotho (klotho) is a protein known for its anti-aging properties and has been shown to delay the onset of age-related diseases. Soluble klotho is produced by cleav...

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Bibliographic Details
Main Authors: Anqi Tang, Yu Zhang, Ling Wu, Yong Lin, Lizeyu Lv, Liangbin Zhao, Bojun Xu, Youqun Huang, Mingquan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1180169/full