Modeling and analysis of the effect of optimal virus control on the spread of HFMD

Abstract A within-host and between-host hand, foot and mouth disease (HFMD) mathematical model is established and the affect of optimal control in its within-host part on HFMD transmission is studied. Through define two basic reproduction numbers, by using the fast-slow system analysis method of tim...

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Bibliographic Details
Main Authors: Hui Wang, Weihua Li, Lei Shi, Gaofang Chen, Zhengwen Tu
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-56839-z