Genome-Wide Screening Identifies Gene AKR1C1 Critical for Resistance to Pirarubicin in Bladder Cancer

Genome-Wide Screening Identifies Gene AKR1C1 Critical for Resistance to Pirarubicin in Bladder Cancer

Non-muscle-invasive bladder cancer (NMIBC) is a common tumor of the urinary system. Given its high rates of recurrence, progression, and drug resistance, NMIBC seriously affects the quality of life and limits the survival time of patients. Pirarubicin (THP) is a bladder infusion chemotherapy drug re...

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Bibliographic Details
Main Authors: Zhenyu Nie, Yuanhui Gao, Mei Chen, Yanling Peng, Na Guo, Hui Cao, Denggao Huang, Xin Gao, Shufang Zhang
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
CRISPR/dCas9-SAM
bladder cancer
pirarubicin
drug resistance
AKR1C1
Online Access:https://www.mdpi.com/2072-6694/15/9/2487

Internet

https://www.mdpi.com/2072-6694/15/9/2487

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