Neurological management and work-up of neurotoxicity associated with CAR T cell therapy

Neurological management and work-up of neurotoxicity associated with CAR T cell therapy

Abstract Introduction Treatment with CD19 chimeric antigen receptor (CAR) T cells is an innovative therapeutic approach for patients with relapsed/refractory diffuse large B cell lymphoma (r/rDLBCL) and B-lineage acute lymphoblastic leukemia (r/rALL). However, convincing therapeutic response rates c...

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Bibliographic Details
Main Authors: Nora Möhn, Viktoria Bonda, Lea Grote-Levi, Victoria Panagiota, Tabea Fröhlich, Christian Schultze-Florey, Mike P. Wattjes, Gernot Beutel, Matthias Eder, Sascha David, Sonja Körner, Günter Höglinger, Martin Stangel, Arnold Ganser, Christian Koenecke, Thomas Skripuletz
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Neurological Research and Practice
Subjects:
Autoimmunity
Neurotoxicity
Immunotherapy
Chimeric Antigen Receptors
T-Lymphocytes
Online Access:https://doi.org/10.1186/s42466-021-00166-5

Internet

https://doi.org/10.1186/s42466-021-00166-5

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