Brain Death in Combination with Warm Ischemic Stress during Isolation Procedures Induces the Expression of Crucial Inflammatory Mediators in the Isolated Islets

Brain Death in Combination with Warm Ischemic Stress during Isolation Procedures Induces the Expression of Crucial Inflammatory Mediators in the Isolated Islets

Tissue factor (TF) and monocyte chemoattractant protein-1 (MCP-1) expressed on the islets have been identified as the main trigger of the instant blood-mediated inflammatory reaction (IBMIR) in islet transplantation. Because the key steps that directly induce TF and MCP-1 remain to be determined, we...

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Bibliographic Details
Main Authors: Yukihiko Saito, Masafumi Goto M.D., Ph.D., Kozue Maya, Norihiko Ogawa, Keisei Fujimori, Yoshimochi Kurokawa, Susumu Satomi
Format: Article
Language:English
Published: SAGE Publishing 2010-06-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X508889

Internet

https://doi.org/10.3727/096368910X508889

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