A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma

A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma

IntroductionDiffuse intrinsic pontine glioma (DIPG), recently reclassified as a subtype of diffuse midline glioma, is a highly aggressive brainstem tumor affecting children and young adults, with no cure and a median survival of only 9 months. Conventional treatments are ineffective, highlighting th...

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Bibliographic Details
Main Authors: Kirti Pandey, Stacie S. Wang, Nicole A. Mifsud, Pouya Faridi, Alexander J. Davenport, Andrew I. Webb, Jarrod J. Sandow, Rochelle Ayala, Michelle Monje, Ryan S. Cross, Sri H. Ramarathinam, Misty R. Jenkins, Anthony W. Purcell
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
DIPG
paediatric brain cancer
proteomics
surfaceome
HLA
immunopeptidomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1192448/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1192448/full

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