Relation of AURKB over-expression to low survival rate in BCRA and reversine-modulated aurora B kinase in breast cancer cell lines

Abstract Background New therapeutic drug for breast cancer (BRCA), especially triple negative BRCA (TNBC), is urgently needed. Even though 2-(4-morpholinoanilino)-6-cyclohexylaminopurine (reversine) is an aurora kinase inhibitor, it also inhibits some cancer cells and human BRCA cells. However, the...

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Bibliographic Details
Main Authors: Di Huang, Yu Huang, Zisheng Huang, Jiefeng Weng, Shuai Zhang, Weili Gu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-019-0885-z