Homologous peptides derived from influenza A, B and C viruses induce variable CD8+ T cell responses with cross‐reactive potential

Homologous peptides derived from influenza A, B and C viruses induce variable CD8+ T cell responses with cross‐reactive potential

Abstract Objective Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally, infecting humans and causing widespread morbidity and mortality. Here, we investigate the T cell response towards an immunodominant IAV epitope, NP265‐273, and its IBV and ICV homologues, presented b...

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Bibliographic Details
Main Authors: Andrea T Nguyen, Hiu Ming Peter Lau, Hannah Sloane, Dhilshan Jayasinghe, Nicole A Mifsud, Demetra SM Chatzileontiadou, Emma J Grant, Christopher Szeto, Stephanie Gras
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical & Translational Immunology
Subjects:
CD8+ T cell
cross‐reactivity
HLA
immune response
immunodominant epitope
Influenza
Online Access:https://doi.org/10.1002/cti2.1422

Internet

https://doi.org/10.1002/cti2.1422

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