Genetic Testing for Steroid-Resistant-Nephrotic Syndrome in an Outbred Population

Genetic Testing for Steroid-Resistant-Nephrotic Syndrome in an Outbred Population

Background: Steroid-resistant nephrotic syndrome (SRNS) is a leading cause of end-stage kidney disease in children and young adults. Despite advances in genomic science that have led to the discovery of >50 monogenic causes of SRNS, there are no clear guidelines for genetic testing in clinica...

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Bibliographic Details
Main Authors: Jennifer D. Varner, Megan Chryst-Stangl, Christopher Imokhuede Esezobor, Adaobi Solarin, Guanghong Wu, Brandon Lane, Gentzon Hall, Asiri Abeyagunawardena, Ayo Matory, Tracy E. Hunley, Jen Jar Lin, David Howell, Rasheed Gbadegesin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pediatrics
Subjects:
focal segmental glomerulosclerosis
genetic testing
monogenic disease
podocyte
steroid-resistant nephrotic syndrome
Online Access:https://www.frontiersin.org/article/10.3389/fped.2018.00307/full

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https://www.frontiersin.org/article/10.3389/fped.2018.00307/full

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