Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer

Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer

Non-small-cell lung cancer (NSCLC) is a typical inflammation-associated cancer, and lung adenocarcinoma (LUAD) is the most common pathological subtype. Epidermal growth factor (EGF) receptor (EGFR) mutations are the most common driver mutations of LUAD, and they have been identified as important the...

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Main Authors: Kai-Ling Lee, Tsung-Ching Lai, Wei-Jiunn Lee, Yu-Chieh Chen, Kuo-Hao Ho, Wen-Yueh Hung, Yi-Chieh Yang, Ming-Hsien Chan, Feng-Koo Hsieh, Chi-Li Chung, Jer-Hwa Chang, Ming-Hsien Chien
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
interleukin-17A
interleukin-17 receptor C
epidermal growth factor receptor
proliferation
non-small-cell lung cancer
Online Access:https://www.mdpi.com/2072-6694/15/13/3288

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https://www.mdpi.com/2072-6694/15/13/3288

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