Influence of Electrospun Fibre Secondary Morphology on Antibiotic Release Kinetic and Its Impact on Antimicrobic Efficacy

Influence of Electrospun Fibre Secondary Morphology on Antibiotic Release Kinetic and Its Impact on Antimicrobic Efficacy

Vascular graft infections are a severe complication in vascular surgery, with a high morbidity and mortality. Prevention and treatment involve the use of antibiotic- or antiseptic-impregnated artificial vascular grafts, but currently, there are no commercially available infection-proof small-diamete...

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Bibliographic Details
Main Authors: Mariella Rosalia, Pietro Grisoli, Rossella Dorati, Enrica Chiesa, Silvia Pisani, Giovanna Bruni, Ida Genta, Bice Conti
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
vascular graft infection
small-diameter vascular graft
tobramycin
secondary fibre morphology
drug release kinetic
drug release modelling
Online Access:https://www.mdpi.com/1422-0067/24/15/12108

Internet

https://www.mdpi.com/1422-0067/24/15/12108

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