rab-27 acts in an intestinal pathway to inhibit axon regeneration in C. elegans.

Injured axons must regenerate to restore nervous system function, and regeneration is regulated in part by external factors from non-neuronal tissues. Many of these extrinsic factors act in the immediate cellular environment of the axon to promote or restrict regeneration, but the existence of long-...

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Bibliographic Details
Main Authors: Alexander T Lin-Moore, Motunrayo J Oyeyemi, Marc Hammarlund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009877