<i>TLR5</i> Variants Are Associated with the Risk for COPD and NSCLC Development, Better Overall Survival of the NSCLC Patients and Increased Chemosensitivity in the H1299 Cell Line

<i>TLR5</i> Variants Are Associated with the Risk for COPD and NSCLC Development, Better Overall Survival of the NSCLC Patients and Increased Chemosensitivity in the H1299 Cell Line

Chronic obstructive pulmonary disease (COPD) is considered as the strongest independent risk factor for lung cancer (LC) development, suggesting an overlapping genetic background in both diseases. A common feature of both diseases is aberrant immunity in respiratory epithelia that is mainly regulate...

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Bibliographic Details
Main Authors: Jurica Baranašić, Maja Šutić, Calogerina Catalano, Gordana Drpa, Stefanie Huhn, Dragomira Majhen, Davor Nestić, Matea Kurtović, Lada Rumora, Martina Bosnar, Andrea Vukić Dugac, Irena Sokolović, Sanja Popovic-Grle, Nada Oršolić, Sanda Škrinjarić-Cincar, Marko Jakopović, Miroslav Samaržija, Alexander N. R. Weber, Asta Försti, Jelena Knežević
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
COPD
NSCLC
TLR5
SNP
survival
chemoresistance
Online Access:https://www.mdpi.com/2227-9059/10/9/2240

Internet

https://www.mdpi.com/2227-9059/10/9/2240

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