Comprehensive allostatic load risk index is associated with increased frontal and left parietal white matter hyperintensities in mid-life cognitively healthy adults

Comprehensive allostatic load risk index is associated with increased frontal and left parietal white matter hyperintensities in mid-life cognitively healthy adults

Abstract To date, there is a considerable heterogeneity of methods to score Allostatic Load (AL). Here we propose a comprehensive algorithm (ALCS) that integrates commonly used approaches to generate AL risk categories and assess associations to brain structure deterioration. In a cohort of cognitiv...

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Bibliographic Details
Main Authors: Ingrid Buller-Peralta, Sarah Gregory, Audrey Low, Maria-Eleni Dounavi, Katie Bridgeman, Georgios Ntailianis, Brian Lawlor, Lorina Naci, Ivan Koychev, Paresh Malhotra, John T. O’Brien, Craig W. Ritchie, Graciela Muniz-Terrera
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49656-3

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https://doi.org/10.1038/s41598-023-49656-3

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