Ultrastructural alterations of intracellular stages and effects on blood forms of Trypanosoma cruzi induced in vivo by 2-amino-5-(1-methyil-5-nitro-2-imidazolyl)-1,3,4 - Thiadiazole

Ultrastructural alterations of intracellular stages and effects on blood forms of Trypanosoma cruzi induced in vivo by 2-amino-5-(1-methyil-5-nitro-2-imidazolyl)-1,3,4 - Thiadiazole

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An electron microscopy study shows that the administration of a single dose (500 mg/kg, p.o.) of 2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1, 3, 4-thiadiazole induces in mice infected with Trypanosoma cruzi results in degenerative lesions of the intracellular stages. Ultrastructural alterations are...

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Bibliographic Details
Main Authors: Thaisa de Almeida Maria, Leny de Sousa Filardi, Zigman Brener
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1984-06-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Trypanosoma cruzi
Nitroimidazol - Tiadiazole
Microscopia eletrônica
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821984000200008&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821984000200008&lng=en&tlng=en

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