3D cell sheets formed via cell-driven buckling-delamination of patterned thin films

Complex geometries such as folds and protrusions in various organs are formed by the wrinkling/buckling of flat epithelial sheets. This morphogenesis is considered to be triggered by mechanical instabilities between the epithelial sheet and the mesenchyme foundation, similar to that observed in non-...

Full description

Bibliographic Details
Main Authors: Tomoko Gowa Oyama, Kotaro Oyama, Hiromi Miyoshi, Mitsumasa Taguchi
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521005293