The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response

Zinc finger proteins are involved in the resolution of immune responses and function by degrading mRNA of inflammatory cytokines. Here the authors show MCPIP3 promotes skin inflammation via modification of cytokine profiles in pDCs and macrophages.

Bibliographic Details
Main Authors: Bo Liu, Jiancheng Huang, Amina Ashraf, Oindrila Rahaman, Jing Lou, Ling Wang, Peiliang Cai, Jinping Wen, Shoaib Anwaar, Xiaoli Liu, Hai Ni, Dipyaman Ganguly, Jijun Zhao, Cliff Y. Yang
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24352-w