Combined transfer of human VEGF165 and HGF genes renders potent angiogenic effect in ischemic skeletal muscle.

Combined transfer of human VEGF165 and HGF genes renders potent angiogenic effect in ischemic skeletal muscle.

Increased interest in development of combined gene therapy emerges from results of recent clinical trials that indicate good safety yet unexpected low efficacy of "single-gene" administration. Multiple studies showed that vascular endothelial growth factor 165 aminoacid form (VEGF165) and...

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Bibliographic Details
Main Authors: Pavel Makarevich, Zoya Tsokolaeva, Alexander Shevelev, Igor Rybalkin, Evgeny Shevchenko, Irina Beloglazova, Tatyana Vlasik, Vsevolod Tkachuk, Yelena Parfyonova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22719942/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22719942/pdf/?tool=EBI

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