Sphingosine kinase 1 overexpression contributes to sunitinib resistance in clear cell renal cell carcinoma

Sphingosine kinase 1 overexpression contributes to sunitinib resistance in clear cell renal cell carcinoma

Sphingosine kinase 1 (SphK1) is the major source of the bioactive lipid and GPCR agonist sphingosine 1-phosphate (S1P). Although alterations in SphK1 expression and activity have been detected in various human malignancies, its potential molecular mechanisms in the development and sunitinib resistan...

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Bibliografische gegevens
Hoofdauteurs: Yunze Xu, Baijun Dong, Jianfeng Wang, Jin Zhang, Wei Xue, Yiran Huang
Formaat: Artikel
Taal:English
Gepubliceerd in: Taylor & Francis Group 2018-12-01
Reeks:OncoImmunology
Onderwerpen:
sphk1
ccrcc
sunitinib resistance
fty720
array
Online toegang:http://dx.doi.org/10.1080/2162402X.2018.1502130

Internet

http://dx.doi.org/10.1080/2162402X.2018.1502130

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