Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma

Summary: Extranodal natural killer/T cell lymphoma, nasal type (ENKTL) is an aggressive lymphoid malignancy with a poor prognosis and lacks standard treatment. Targeted therapies are urgently needed. Here we systematically investigated the druggable mechanisms through chemogenomic screening and iden...

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Bibliographic Details
Main Authors: Chuanxu Liu, Xinyu Ding, Gaoyang Li, Youping Zhang, Yubao Shao, Linyi Liu, Wenhao Zhang, Yujie Ma, Wenbin Guan, Lifeng Wang, Zhongli Xu, YungTing Chang, Yongqiang Zhang, Biao Jiang, Qianqian Yin, Rong Tao
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014463