A Novel Tandem-Tag Purification Strategy for Challenging Disordered Proteins

A Novel Tandem-Tag Purification Strategy for Challenging Disordered Proteins

Intrinsically disordered proteins (IDPs) lack well-defined 3D structures and can only be described as ensembles of different conformations. This high degree of flexibility allows them to interact promiscuously and makes them capable of fulfilling unique and versatile regulatory roles in cellular pro...

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Bibliographic Details
Main Authors: Attila Mészáros, Kevin Muwonge, Steven Janvier, Junaid Ahmed, Peter Tompa
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomolecules
Subjects:
intrinsically disordered proteins (IDPs)
protein purification
affinity chromatography
Tau
androgen receptor (AF1)
Online Access:https://www.mdpi.com/2218-273X/12/11/1566

Internet

https://www.mdpi.com/2218-273X/12/11/1566

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