NiH-catalyzed asymmetric hydroalkynylation of α,β-unsaturated amides

An enantioselective NiH-catalyzed hydroalkynylation of α,β-unsaturated amides is reported. A wide range of α,β-unsaturated amides and bromoalkynes are suitable substrates for this reaction, which proceeds under mild conditions, allowing access to a variety of enantioenriched chiral β-alkynyl amides....

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Bibliographic Details
Main Authors: Yuanzheng Cheng, Zhuofan Gui, Ran Tao, You Wang, Shaolin Zhu
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2022-11-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554922000291