T. gondii rhoptry protein ROP18 induces apoptosis of neural cells via endoplasmic reticulum stress pathway

T. gondii rhoptry protein ROP18 induces apoptosis of neural cells via endoplasmic reticulum stress pathway

Abstract Background The neurotropic parasite T. gondii is widespread among mammalian hosts including humans. During the course of T. gondii infection, the central nervous system is the most commonly damaged of all invasive organs. The polymorphic rhoptry protein ROP18 has been identified as a key fa...

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Bibliographic Details
Main Authors: Lijuan Wan, Lingli Gong, Wei Wang, Ran An, Meijuan Zheng, Zongru Jiang, Yuewen Tang, Yihua Zhang, He Chen, Li Yu, Jilong Shen, Jian Du
Format: Article
Language:English
Published: BMC 2015-10-01
Series:Parasites & Vectors
Subjects:
T. gondii
ROP18
ER stress
Apoptosis
Online Access:https://doi.org/10.1186/s13071-015-1103-z

Internet

https://doi.org/10.1186/s13071-015-1103-z

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