Discovery and Structural Characterization of Impurities in the Synthesis of Darolutamide Intermediate
Darolutamide is an important drug for the treatment of prostate cancer. When studying its synthesis process, three impurities A, B, and C were discovered and purified in the first step of Suzuki coupling and the second step of hydrolysis deprotection reactions. Impurities A and B came from the first...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Science Press
2024-03-01
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| Series: | Chinese Journal of Magnetic Resonance |
| Subjects: | |
| Online Access: | http://121.43.60.238/bpxzz/article/2024/1000-4556/1000-4556-41-1-56.shtml |