Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP<sub>82–98</sub>) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II
Background: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system. MS is a T cell-mediated disease characterized by the proliferation, infiltration, and attack of the myelin sheath by immune cells. Previous studies have shown that cyclization provides molecules with strict...
Hauptverfasser: | , , , , , , , |
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Format: | Artikel |
Sprache: | English |
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MDPI AG
2018-12-01
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Schriftenreihe: | Brain Sciences |
Schlagworte: | |
Online Zugang: | https://www.mdpi.com/2076-3425/8/12/213 |