Comprehensive Volumetric Analysis of Mecp2-Null Mouse Model for Rett Syndrome by T2-Weighted 3D Magnetic Resonance Imaging

Comprehensive Volumetric Analysis of Mecp2-Null Mouse Model for Rett Syndrome by T2-Weighted 3D Magnetic Resonance Imaging

Rett syndrome (RTT) is a severe progressive neurodevelopmental disorder characterized by various neurological symptoms. Almost all RTT cases are caused by mutations in the X-linked methyl-CpG-binding protein 2 (MeCP2) gene, and several mouse models have been established to understand the disease. Ho...

Full description

Bibliographic Details
Main Authors: Yuichi Akaba, Tadashi Shiohama, Yuji Komaki, Fumiko Seki, Alpen Ortug, Daisuke Sawada, Wataru Uchida, Koji Kamagata, Keigo Shimoji, Shigeki Aoki, Satoru Takahashi, Takeshi Suzuki, Jun Natsume, Emi Takahashi, Keita Tsujimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Neuroscience
Subjects:
Rett syndrome
methyl-CpG-binding protein 2
magnetic resonance imaging
brain structure
volumetric analysis
neurodevelopmental disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.885335/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.885335/full

Similar Items