Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota

Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota

Abstract Background The influence of age on basophils is poorly understood, as well as the effect of aging-associated microbiota on basophils. Therefore, we studied the influence of aging and aging-associated microbiota on basophil frequency and phenotype, and differentiation from basophil precursor...

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Bibliographic Details
Main Authors: Adriaan A. van Beek, Floris Fransen, Ben Meijer, Paul de Vos, Edward F. Knol, Huub F. J. Savelkoul
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Immunity & Ageing
Subjects:
Aging
Basophils
Immunity
Microbiota
Bone marrow
Spleen
Online Access:http://link.springer.com/article/10.1186/s12979-018-0135-6

Internet

http://link.springer.com/article/10.1186/s12979-018-0135-6

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