Acetylation of p65Lys310 by p300 in macrophages mediates anti-inflammatory property of berberine

Acetylation of p65Lys310 by p300 in macrophages mediates anti-inflammatory property of berberine

Nuclear factor (NF)-κB plays a pivotal role in the regulation of inflammatory response in macrophages. Berberine (BBR), which is an active constituent isolated from Coptis rhizome, possesses a prominent anti-inflammatory activity. Here we show that BBR changes the global acetylation landscape in LPS...

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Bibliographic Details
Main Authors: Shuchen Zhang, Pingyuan Xu, Ziwei Zhu, Lingyan Zhou, Jiao Li, Ruonan Zhou, Yue Kan, Yaru Li, Xizhong Yu, Juan Zhao, Yu Jin, Jing Yan, Penghua Fang, Wenbin Shang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Subjects:
Berberine
p65
p300
Inflammatory response
Macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723001052

Internet

http://www.sciencedirect.com/science/article/pii/S2213231723001052

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