Frameshift mutation in myostatin gene by zinc-finger nucleases results in a significant increase in muscle mass in Meishan sows

Frameshift mutation in myostatin gene by zinc-finger nucleases results in a significant increase in muscle mass in Meishan sows

Myostatin (MSTN) is a negative regulator of skeletal muscle growth and development. A significant increase in skeletal muscle was observed in Mstn-/- mice compared with wild-type mice. So far, there has been no report on porcine MSTN mutations leading to skeletal muscle hypertrophy. In this report a...

Full description

Bibliographic Details
Main Authors: Hanfang Bi, Shanshan Xie, Chunbo Cai, Lili Qian, Shengwang Jiang, Gaojun Xiao, Biao Li, Xiang Li, Wentao Cui
Format: Article
Language:English
Published: Czech Academy of Agricultural Sciences 2020-05-01
Series:Czech Journal of Animal Science
Subjects:
mstn
zfn-edited
skeletal muscle
lean meat yield
myofibres
Online Access:https://cjas.agriculturejournals.cz/artkey/cjs-202005-0004_frameshift-mutation-in-x202f-myostatin-gene-by-x202f-zinc-finger-nucleases-results-in-x202f-a-significant-in.php

Internet

https://cjas.agriculturejournals.cz/artkey/cjs-202005-0004_frameshift-mutation-in-x202f-myostatin-gene-by-x202f-zinc-finger-nucleases-results-in-x202f-a-significant-in.php

Similar Items