Wnt/β-Catenin Signaling Activation Induces Differentiation in Human Limbal Epithelial Stem Cells Cultured Ex Vivo

Wnt/β-Catenin Signaling Activation Induces Differentiation in Human Limbal Epithelial Stem Cells Cultured Ex Vivo

Human limbal epithelial stem cells (hLESCs) continuously replenish lost or damaged human corneal epithelial cells. The percentage of stem/progenitor cells in autologous ex vivo expanded tissue is essential for the long-term success of transplantation in patients with limbal epithelial stem cell defi...

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Bibliographic Details
Main Authors: Jovana Bisevac, Kirankumar Katta, Goran Petrovski, Morten Carstens Moe, Agate Noer
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
limbal epithelial stem cells
Wnt/β-catenin signaling
stemness
proliferation
differentiation
Online Access:https://www.mdpi.com/2227-9059/11/7/1829

Internet

https://www.mdpi.com/2227-9059/11/7/1829

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