Development and validation of a simple, fast and sensitive liquid chromatography-tandem mass spectrometry method to establish reference intervals for 24-h urinary free normetanephrine, metanephrine and methoxytyramine
Objective: To develop and validate a rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to detect urinary free metanephrines and methoxytyramine, establishing reference intervals. Methods: Urine samples were diluted with isotope internal standard solution, then analyzed directly...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-03-01
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Series: | Practical Laboratory Medicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352551724000040 |