Development and validation of a simple, fast and sensitive liquid chromatography-tandem mass spectrometry method to establish reference intervals for 24-h urinary free normetanephrine, metanephrine and methoxytyramine

Objective: To develop and validate a rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to detect urinary free metanephrines and methoxytyramine, establishing reference intervals. Methods: Urine samples were diluted with isotope internal standard solution, then analyzed directly...

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Bibliographic Details
Main Authors: Yan Song, Runhao Xu, Dan Liu, Jie Zhang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Practical Laboratory Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551724000040