Universal antibody targeting the highly conserved fusion peptide provides cross-protection in mice

Universal antibody targeting the highly conserved fusion peptide provides cross-protection in mice

Influenza is a major public health concern causing millions of hospitalizations every year. The current vaccines need annual updating based on prediction of likely strains in the upcoming season. However, mismatches between vaccines and the actual circulating viruses can occur, reducing vaccine effe...

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Bibliographic Details
Main Authors: Abenaya Muralidharan, Caroline Gravel, Greg Harris, Anwar M. Hashem, Wanyue Zhang, David Safronetz, Gary Van Domselaar, Florian Krammer, Simon Sauve, Michael Rosu-Myles, Lisheng Wang, Wangxue Chen, Xuguang Li
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
influenza
universal antibody
uni-1
antibody-dependent cellular cytotoxicity (adcc)
cross-protection
Online Access:http://dx.doi.org/10.1080/21645515.2022.2083428

Internet

http://dx.doi.org/10.1080/21645515.2022.2083428

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