Systematic review of antitumour efficacy and mechanism of metformin activity in prostate cancer models

Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use...

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Bibliographic Details
Main Authors: Nan Fang Wang, Toni Rose Jue, Jeff Holst, Jennifer H. Gunter
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:BJUI Compass
Subjects:
Online Access:https://doi.org/10.1002/bco2.187