Engineered Recombinant Single Chain Variable Fragment of Monoclonal Antibody Provides Protection to Chickens Infected with H9N2 Avian Influenza

Engineered Recombinant Single Chain Variable Fragment of Monoclonal Antibody Provides Protection to Chickens Infected with H9N2 Avian Influenza

Passive immunisation with neutralising antibodies can be a potent therapeutic strategy if used pre- or post-exposure to a variety of pathogens. Herein, we investigated whether recombinant monoclonal antibodies (mAbs) could be used to protect chickens against avian influenza. Avian influenza viruses...

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Bibliographic Details
Main Authors: Deimante Lukosaityte, Jean-Remy Sadeyen, Angita Shrestha, Joshua E. Sealy, Sushant Bhat, Pengxiang Chang, Paul Digard, Munir Iqbal
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
single chain variable fragment antibody (scfv), passive immunisation
recombinant antibodies
neutralizing antibodies
influenza virus
chicken protection
Online Access:https://www.mdpi.com/2076-393X/8/1/118

Internet

https://www.mdpi.com/2076-393X/8/1/118

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