Alterations in N-glycosylation of HCV E2 Protein in Children Patients with IFN-RBV Therapy Failure

Alterations in N-glycosylation of HCV E2 Protein in Children Patients with IFN-RBV Therapy Failure

The glycosylation of viral envelope proteins plays an important role in virus biology and the immune response of the host to infection. Hepatitis C virus (HCV) envelope proteins E1 and E2, key players in virus entry and spread, are highly N-glycosylated and possess 4 (5 in certain genotypes) to 11 c...

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Bibliographic Details
Main Authors: Karolina Zimmer, Alicja M. Chmielewska, Paulina Jackowiak, Marek Figlerowicz, Krystyna Bienkowska-Szewczyk
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pathogens
Subjects:
hepatitis C virus
glycoproteins
glycosylation
neutralization antibodies
response to therapy
Online Access:https://www.mdpi.com/2076-0817/13/3/256

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https://www.mdpi.com/2076-0817/13/3/256

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