Signaling Dynamics of TSHR-Specific CAR-T Cells Revealed by FRET-Based Biosensors

Although most patients with thyroid cancers have good prognosis and long-term survival, some patients are refractory to traditional therapeutic approaches and face a high risk of mortality. CAR-T therapy provides an attractive strategy to treat these patients. Considering the limited expression in t...

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Bibliographic Details
Main Authors: Jing Zhou, Jiangqing Chen, Yanjie Huang, Xiaofei Gao, Chun Zhou, Xianhui Meng, Jie Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.845319/full