Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice

Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice

Yi Liu,1 David Quintanar Guerrero,2 David Lechuga-Ballesteros,3 Mingdian Tan,1 Faiz Ahmad,1 Bilal Aleiwi,4 Edmund Lee Ellsworth,4 Bin Chen,4 Mei-Sze Chua,1 Samuel So1 1Department of Surgery, School of Medicine, Stanford University, Stanford, CA, USA; 2Laboratorio de Investigación y Posgrado en Tecno...

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Bibliographic Details
Main Authors: Liu Y, Guerrero DQ, Lechuga-Ballesteros D, Tan M, Ahmad F, Aleiwi B, Ellsworth EL, Chen B, Chua MS, So S
Format: Article
Language:English
Published: Dove Medical Press 2024-03-01
Series:International Journal of Nanomedicine
Subjects:
niclosamide
self-microemulifying drug delivery system
smedds
oral bioavailability
drug repurposing
hepatocellular carcinoma
Online Access:https://www.dovepress.com/lipid-based-self-microemulsion-of-niclosamide-achieved-enhanced-oral-d-peer-reviewed-fulltext-article-IJN

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https://www.dovepress.com/lipid-based-self-microemulsion-of-niclosamide-achieved-enhanced-oral-d-peer-reviewed-fulltext-article-IJN

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