Non-invasive in vivo sensing of bacterial implant infection using catalytically-optimised gold nanocluster-loaded liposomes for urinary readout

Abstract Staphylococcus aureus is a leading cause of nosocomial implant-associated infections, causing significant morbidity and mortality, underscoring the need for rapid, non-invasive, and cost-effective diagnostics. Here, we optimise the synthesis of renal-clearable gold nanoclusters (AuNCs) for...

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Bibliographic Details
Main Authors: Kaili Chen, Adrian Najer, Patrick Charchar, Catherine Saunders, Chalaisorn Thanapongpibul, Anna Klöckner, Mohamed Chami, David J. Peeler, Inês Silva, Luca Panariello, Kersti Karu, Colleen N. Loynachan, Leah C. Frenette, Michael Potter, John S. Tregoning, Ivan P. Parkin, Andrew M. Edwards, Thomas B. Clarke, Irene Yarovsky, Molly M. Stevens
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53537-2