Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

<p>Abstract</p> <p>Background</p> <p>To study the role of microRNA (miRNA) in the regulation of Chinese hamster ovary (CHO) cell growth, qPCR, microarray and quantitative LC-MS/MS analysis were utilised for simultaneous expression profiling of miRNA, mRNA and protein. T...

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Bibliographic Details
Main Authors: Clarke Colin, Henry Michael, Doolan Padraig, Kelly Shane, Aherne Sinead, Sanchez Noelia, Kelly Paul, Kinsella Paula, Breen Laura, Madden Stephen F, Zhang Lin, Leonard Mark, Clynes Martin, Meleady Paula, Barron Niall
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Genomics
Subjects:
Chinese hamster ovary
CHO cells
Growth rate
MicroRNA
mRNA
Microarray
Proteomics
Online Access:http://www.biomedcentral.com/1471-2164/13/656

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http://www.biomedcentral.com/1471-2164/13/656

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