<i>ARID1A</i> and <i>CTNNB1</i>/β-Catenin Molecular Status Affects the Clinicopathologic Features and Prognosis of Endometrial Carcinoma: Implications for an Improved Surrogate Molecular Classification

<i>ARID1A</i> and <i>CTNNB1</i>/β-Catenin Molecular Status Affects the Clinicopathologic Features and Prognosis of Endometrial Carcinoma: Implications for an Improved Surrogate Molecular Classification

The collaborative Cancer Genome Atlas (TCGA) project identified four distinct prognostic groups of endometrial carcinoma (EC) based on molecular alterations: (i) the ultramutated subtype that encompasses <i>POLE</i> mutated (<i>POLE</i>) cases; (ii) the hypermutated subtype,...

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Bibliographic Details
Main Authors: Antonio De Leo, Dario de Biase, Jacopo Lenzi, Giovanna Barbero, Daniela Turchetti, Marco Grillini, Gloria Ravegnini, Sabrina Angelini, Claudio Zamagni, Sara Coluccelli, Giulia Dondi, Pierandrea De Iaco, Anna Myriam Perrone, Giovanni Tallini, Donatella Santini, Claudio Ceccarelli
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
endometrial cancer
molecular classification
<i>ARID1A</i>
<i>CTNNB1</i>/β-catenin
prognosis
high-risk endometrial cancer
Online Access:https://www.mdpi.com/2072-6694/13/5/950

Internet

https://www.mdpi.com/2072-6694/13/5/950

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