Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression

ABSTRACT Conjugation of small ubiquitin-like modifiers (SUMOs) to substrate proteins is a posttranslational protein modification that affects a diverse range of physiological processes. Global inhibition of SUMO conjugation in mice results in embryonic lethality, reflecting the importance of the SUM...

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Bibliographic Details
Main Authors: Andreia Lee, Yiping Zhu, Yosef Sabo, Stephen P. Goff
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01856-19