Knockout of angiotensin converting enzyme-2 receptor leads to morphological aberrations in rodent olfactory centers and dysfunctions associated with sense of smell

Knockout of angiotensin converting enzyme-2 receptor leads to morphological aberrations in rodent olfactory centers and dysfunctions associated with sense of smell

Neuronal morphological characterization and behavioral phenotyping in mouse models help dissecting neural mechanisms of brain disorders. Olfactory dysfunctions and other cognitive problems were widely reported in asymptomatic carriers and symptomatic patients infected with Severe Acute Respiratory S...

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Bibliographic Details
Main Authors: Sarang Mahajan, Deepshikha Sen, Anantu Sunil, Priyadharshini Srikanth, Shruti D. Marathe, Karishma Shaw, Mahesh Sahare, Sanjeev Galande, Nixon M. Abraham
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neuroscience
Subjects:
ACE2 receptor
gene knockout
CRISPR-Cas9
olfactory system
sensory and cognitive deficits
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1180868/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1180868/full

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